Smart “on-off” responsive drug delivery nanosystems for potential imaging diagnosis and targeted tumor therapy

Cancer is one of the most concerned diseases in the world, where there is still no reported specifically targeted drugs with high effect. In this study, mesoporous silica with a large pore size of 25.25 nm and magnetic cores was prepared as a carrier of doxorubicin for anti-cancer drug delivery. Besides its superior biocompatibility properties and functional surface, the large mesopores provided enough space for multiple chemical modification...