Downregulation of miroRNA‐141 mediates acquired resistance to trastuzumab and is associated with poor outcome in breast cancer by upregulating the expression of ERBB4

Background microRNAs are involved in the control of cell growth and apoptosis; they also play an essential role in resistance towards trastuzumab, in breast cancer. The objective of this study was to identify differentially expressed microRNA(s) and explore its therapeutic role in treatment of the disease. Methods Real‐time polymerase chain reaction (RT‐PCR) was performed to identify the virtual microRNA (miRNA) involved in breast cancer cells...