Protein-Engineered Nanoscale Micelles for Dynamic 19F Magnetic Resonance and Therapeutic Drug Delivery

Volume: 13, Issue: 3, Pages: 2969 - 2985
Published: Feb 13, 2019
Abstract
Engineered proteins provide an interesting template for designing fluorine-19 (19F) magnetic resonance imaging (MRI) contrast agents, yet progress has been hindered by the unpredictable relaxation properties of fluorine. Herein, we present the biosynthesis of a protein block copolymer, termed “fluorinated thermoresponsive assembled protein” (F-TRAP), which assembles into a monodisperse nanoscale micelle with interesting 19F NMR properties and...
Paper Details
Title
Protein-Engineered Nanoscale Micelles for Dynamic 19F Magnetic Resonance and Therapeutic Drug Delivery
Published Date
Feb 13, 2019
Journal
Volume
13
Issue
3
Pages
2969 - 2985
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