MicroRNA‐let‐7c suppresses hepatitis C virus replication by targeting Bach1 for induction of haem oxygenase‐1 expression

Summary Micro RNA s are small noncoding RNA s that are central factors between hepatitis C virus ( HCV ) and host cellular factors for viral replication and liver disease progression, including liver fibrosis, cirrhosis and hepatocellular carcinoma. In the present study, we found that overexpressing miR‐let‐7c markedly reduced HCV replication because it induced haem oxygenase‐1 ( HO ‐1) expression by targeting HO ‐1 transcriptional repressor...