Synthesis and colloidal characterization of folic acid-modified PEG-b-PCL Micelles for methotrexate delivery

Volume: 177, Pages: 228 - 234
Published: May 1, 2019
Abstract
Hydrophobic drugs, such as methotrexate, are not easily delivered into the human body. Therefore, the use of amphiphilic nanoplatforms to the transport of these drugs through the bloodstream is a challenge. While the hydrophobic region interacts with the drug, the hydrophilic outer layer enhances its bioavailability and circulation time. Poly (ethylene glycol)-block-poly(ε-caprolactone) PEG-b-PCL micelles are biodegradable and biocompatible,...
Paper Details
Title
Synthesis and colloidal characterization of folic acid-modified PEG-b-PCL Micelles for methotrexate delivery
Published Date
May 1, 2019
Volume
177
Pages
228 - 234
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