Internal medicine

Radiology

Pathology

Liver disease

Disease

Fibrosis

Liver fibrosis

Gold standard (test)

Biology

Gastroenterology

Magnetic resonance imaging

Ultrasound

Stage (stratigraphy)

Paleontology

Cirrhosis

Biopsy

Elastography

Liver biopsy

Steatosis

Transient elastography

Fatty liver

Chronic liver disease

Magnetic resonance elastography

Medicine

Journal of Hepatology

Even though alcohol-related liver disease (ALD) is a major cause of severe liver disease worldwide, most patients with ALD are diagnosed at the decompensation stage. Liver biopsy is still considered the gold standard for establishing a definite diagnosis and assessing the fibrosis stage of ALD, but it is an invasive procedure, associated with significant morbidity. During the last decade, non-invasive tests have been developed to estimate the severity of liver fibrosis and steatosis. Measurement of liver stiffness by transient elastography has become the most commonly used non-invasive parameter to evaluate fibrosis.

Non-invasive diagnosis and biomarkers in alcohol-related liver disease