26. Stepping validation of “knowledge-based” models for semi-automatic plan optimization: The case of concomitant treatment of pelvic nodes and prostatic bed in post-prostatectomy radiotherapy

Purpose To develop and apply a stepping validation approach for Knowledge-based (KB) models for planning optimization, starting from the complex and clinically relevant case of the treatment of pelvic nodes and prostate + seminal-vesicles bed in post-prostatectomy patients (pts). Methods Fifty-two VMAT (Varian, RapidArc) plans optimized by two planners (reference of the protocol) were selected to generate KB-model using the RapidPlan tool...