Cellular senescence in bone
Abstract
Cellular senescence refers to a process induced by various types of stress that causes irreversible cell cycle arrest and distinct cellular alterations, including profound changes in gene expression, metabolism, and chromatin organization as well as activation/reinforcement of anti-apoptotic pathways and development of a pro-inflammatory secretome or senescence-associated secretory phenotype (SASP). However, because of challenges and technical...
Paper Details
Title
Cellular senescence in bone
Published Date
Apr 1, 2019
Journal
Volume
121
Pages
121 - 133
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Notes
History