Review paper
Innate immune-responses and their role in driving autoimmunity
Abstract
Autoimmunity and autoimmune diseases were always considered to be driven mainly by adaptive immune responses, namely by auto-reactive B and T cell over-activity. The continuous stimulation of dendritic cells by autoantigens increases B cell activity, driving auto-reactive B cells to increase the production of autoantibodies and of pro-inflammatory cytokines. On the other hand, a subset of dendritic cells is established being of tolerogenic...
Paper Details
Title
Innate immune-responses and their role in driving autoimmunity
Published Date
Mar 1, 2019
Journal
Volume
18
Issue
3
Pages
306 - 311
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