Purpose:To compare the infectious contact lens–related corneal ulcer (CLRU) and non-CLRU cases at Saint Louis University.Methods:Retrospective review of corneal ulcer cases identified by search of the ophthalmology and microbiology department databases between 1999 and 2016.Results:Six hundred seven
To review the epidemiology, risk factors, microbiologic spectrum, and treatment of microbial keratitis during a 5-year period at an urban public hospital in comparison with an adjacent private university practice. Retrospective chart review in the 5-year interval, 2009 through 2014. Primary outcome measures included patient age at presentation, best-corrected visual acuity (BCVA), risk factors, culture and sensitivities, treatment, and complication occurrence. A total of 528 eyes with microbial ...
Purpose of reviewThis article reviews the literature on past and recent trends in contact lens-related microbial keratitis from bacterial, fungal, and Acanthamoeba infections.Recent findingsContact lens wear is the most important risk factor for microbial keratitis. Despite increased use of daily di
Importance The Antibiotic Resistance Monitoring in Ocular Microorganisms (ARMOR) study is the only ongoing nationwide antibiotic resistance surveillance program specific to ocular pathogens. Objective To report resistance rates and trends among common ocular isolates collected during the first 5 years of the ARMOR study. Design, Setting, and Participants This antibiotic resistance surveillance study was performed at an independent central laboratory. Clinical centers across the United States wer...
Abstract To report the distribution and trends in microbiological and antibiotic sensitivity patterns of infectious keratitis in a 10-year period at a reference center in Mexico City. In this retrospective observational case series, samples were obtained from corneas with a diagnosis of infectious keratitis from January 2002 to December 2011 at the Institute of Ophthalmology "Conde de Valenciana" in Mexico City. Results of cultures, stains, and specific sensitivity/resistance antibiograms for ea...
#1Daniel Sand(SC: University of Southern California)H-Index: 1
#2Rosemary C. She(SC: University of Southern California)H-Index: 21
Last. Hugo Y. Hsu(UCLA: University of California, Los Angeles)H-Index: 13
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Objective To evaluate the spectrum and antibiotic susceptibility panel of infectious keratitis at a major tertiary care referral eye center and a major county hospital in Southern California. Design Retrospective case series. Participants All cultured infectious keratitis cases from July 1, 2008, through December 31, 2012, from the Doheny Eye Institute (DEI) and the Los Angeles County + University of Southern California Medical Center (LAC+USC) were evaluated. Methods Microbiology records were r...
: Keratitis, inflammation of the cornea, can result in partial or total loss of vision and can result from infectious agents (e.g., microbes including bacteria, fungi, amebae, and viruses) or from noninfectious causes (e.g., eye trauma, chemical exposure, and ultraviolet exposure). Contact lens wear is the major risk factor for microbial keratitis; outbreaks of Fusarium and Acanthamoeba keratitis have been associated with contact lens multipurpose solution use, and poor contact lens hygiene is a...
PURPOSE: To evaluate the changes and trends in the number and characteristics of contact lens-related ulcers (CLRUs) and to compare the results with those of previously published series at our institution. METHODS: Medical records of all patients diagnosed with presumed bacterial corneal ulcers seen at the Cornea Service, Wills Eye Institute, between January 1, 2004, and December 31, 2007, were retrospectively reviewed. RESULTS: Five hundred seven corneal ulcers were identified. Of these, 223 (4...
Objective To review the distribution, current trends, and resistance patterns of bacterial keratitis isolates in Toronto over the last 11 years. Design Retrospective, observational, case series. Participants Microbiology records of suspected bacterial keratitis cases that underwent a diagnostic corneal scraping and cultures from January 1, 2000, through December 31, 2010, were reviewed. Methods Culture results and antibiotic sensitivity profiles were reviewed and analyzed. Main Outcome Measures ...
Purpose: To describe the trend of Acanthamoeba keratitis case reports following an outbreak and the recall of a multipurpose contact lens disinfection solution. Acanthamoeba keratitis is a serious eye infection caused by the free-living amoeba Acanthamoeba that primarily affects contact lens users.Methods: A convenience sample of 13 ophthalmology centers and laboratories in the USA, provided annual numbers of Acanthamoeba keratitis cases diagnosed between 1999–2009 and monthly numbers of cases d...
Objective Fungal keratitis is a serious ocular infection that is considered to be rare among contact lens wearers. The recent Fusarium keratitis outbreak raised questions regarding the background rate of Fusarium -related keratitis and other fungal keratitis in this population. Design Retrospective, multicenter case series. Participants Six hundred ninety-five cases of fungal keratitis cases who presented to 1 of 10 tertiary medical centers from 2001 to 2007. Methods Ten tertiary care centers in...
Last. Vishal Jhanji(University of Pittsburgh)H-Index: 32
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Purpose:To characterize the risk factors, clinical presentations, management choices, and outcomes of Proteus mirabilis keratitis.Methods:In this retrospective study, 26 culture-proven cases of P. mirabilis infections were diagnosed and treated between 1998 and 2019 at the University of Pittsburgh M
Abstract Contact lens-related complications are common, affecting around one third of wearers, although most are mild and easily managed. Contact lenses have well-defined anatomical and physiological effects on the ocular surface and can result in other consequences due to the presence of a biologically active material. A contact lens interacts with the tear film, ocular surface, skin, endogenous and environmental microorganisms, components of care solutions and other antigens which may result i...
Abstract Purpose To evaluate the bacterial spectrum and antimicrobial susceptibilities of pathogens isolated from contact lens-related bacterial keratitis cases in a large academic Greek hospital. Methods All adult patients with positive corneal scrapings or contact lens culture between 2007 and 2016 at the University Hospital of Heraklion, Greece, were retrospectively identified through a local microbiology database and their medical records were reviewed. Results A total of 240 isolates were r...
Last. Mark D. P. Willcox(UNSW: University of New South Wales)H-Index: 80
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Frequent replacement contact lenses made from the etafilcon A hydrogel lens material were introduced onto the market over 30 years ago, and etafilcon A remains the most widely used hydrogel lens material today. Although the prescribing of silicone hydrogel lenses is increasing, millions of lens wearers globally have been wearing hydrogel lenses for many years and exhibit a physiologically-stable 'quiet eye', with a low profile of adverse events. Hydrogel lenses are demonstrated to maintain a low...