Blood vs sputum eosinophils as predictors of exacerbations in a cohort of severe asthmatics

Eosinophilic inflammation represents the pathophysiologic background of severe asthma in the majority of these patients. The best tool for assessing eosinophilic inflammation in severe asthma (blood or sputum eosinophils, Fractional exhaled Nitric Oxide [FeNO]) is still poorly defined, as well as whether these biomarkers are associated with different clinical severity features. 77 patients with severe asthma, after a long follow-up in order to...