Safety and efficacy of reduced dose intrapleural alteplase and DNAase for pleural infection

Published: Sep 15, 2018
Abstract
Introduction: The efficacy of intrapleural alteplase 10mg and dornase alfa (DNase) 5mg in pleural infection was established in the MIST-2 trial. Popowicz N et al suggested that alteplase could be reduced to 5mg (1). Aims and Objectives: To assess the efficacy and safety of 2.5mg of alteplase with 5mg DNase. Methods: All patients with pleural infection at St Thomas’ Hospital, London treated with intrapleural fibrinolysis were...
Paper Details
Title
Safety and efficacy of reduced dose intrapleural alteplase and DNAase for pleural infection
Published Date
Sep 15, 2018
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