Aryl hydrocarbon receptor pathway participates in myocardial ischemia reperfusion injury by regulating mitochondrial apoptosis

Reducing ischemia reperfusion (I/R) injury has been a major challenge in the treatment of cardiovascular disease. It is widely accepted that mitochondrial apoptosis is an important link in myocardial infarction induced by I/R damage. Studies suggested that aryl hydrocarbon receptor (AhR) pathway plays an important role in the development and function of the cardiovascular system and regulating the mitochondrial homeostasis. AhR played a critical...