Original paper
Purge Haplotigs: allelic contig reassignment for third-gen diploid genome assemblies
Abstract
Recent developments in third-gen long read sequencing and diploid-aware assemblers have resulted in the rapid release of numerous reference-quality assemblies for diploid genomes. However, assembly of highly heterozygous genomes is still problematic when regional heterogeneity is so high that haplotype homology is not recognised during assembly. This results in regional duplication rather than consolidation into allelic variants and can cause...
Paper Details
Title
Purge Haplotigs: allelic contig reassignment for third-gen diploid genome assemblies
Published Date
Nov 29, 2018
Journal
Volume
19
Issue
1
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Notes
History