Original paper
Lipocalin-2 Functions as Inhibitor of Innate Resistance to Mycobacterium tuberculosis
Abstract
Lipocalin-2 is a constituent of the neutrophil secondary granules and is expressed de novo by macrophages and epithelium in response to inflammation. Lipocalin-2 acts in a bacteriostatic fashion by binding iron-loaded siderophores required for bacterial growth. Mycobacterium tuberculosis (M.tb) produces siderophores that can be bound by lipocalin-2. The impact of lipocalin-2 in the innate immune response toward extracellular bacteria has been...
Paper Details
Title
Lipocalin-2 Functions as Inhibitor of Innate Resistance to Mycobacterium tuberculosis
Published Date
Nov 26, 2018
Journal
Volume
9
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Notes
History