Frontiers in Immunology
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#1Fadel M. GarishahH-Index: 2
#2Nils RotherH-Index: 9
Last. Quirijn de MastH-Index: 22
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#1Marc A. Niles (Paul Ehrlich Institute)
#2Patricia Gogesch (Paul Ehrlich Institute)H-Index: 3
Last. Martina Anzaghe (Paul Ehrlich Institute)H-Index: 6
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The exact role of innate immune cells upon infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and their contribution to the formation of the corona virus-induced disease (COVID)-19 associated cytokine storm is not yet fully understood. We show that human in vitro differentiated myeloid dendritic cells (mDC) as well as M1 and M2 macrophages are susceptible to infection with SARS-CoV-2 but are not productively infected. Furthermore, infected mDC, M1 and M2 macrophages show...
#1Hui Li (Sichuan University)H-Index: 5
#2Hailing Liu (Sichuan University)H-Index: 3
Last. Hong Wu (Sichuan University)H-Index: 22
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The existence of intratumoral tertiary lymphoid structure (iTLS) has been reported to correlative with favorable clinical outcomes for patients with hepatocellular carcinoma (HCC). However, little is known about the role of peritumoral TLS (pTLS). This study aimed to investigate the prognostic role of pTLS either alone or jointly with iTLS and the potential association with local immune response in HCC. The formation and cellular composition of TLS was evaluated by hematoxylin & eosin and immuno...
#1Sarah DellièreH-Index: 8
#2Magalie DuchateauH-Index: 11
Last. Vishukumar AimaniandaH-Index: 30
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#1Patricia Zadorosnei Rebutini (PUCPR: Pontifícia Universidade Católica do Paraná)H-Index: 2
Last. Lucia de Noronha (PUCPR: Pontifícia Universidade Católica do Paraná)H-Index: 17
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Since the beginning of the pandemic, few papers describe the placenta's morphological and morphometrical features in SARS-CoV-2 positive pregnant women. Alterations such as low placental weight, accelerated villous maturation, decidual vasculopathy, infarcts, thrombosis of fetal placental vessels, and chronic histiocytic intervillositis (CHI) have been described. Objective: To analyze clinical data and the placental morphological and morphometric changes of pregnant women infected with SARS-CoV-...
#1Sophia GiangH-Index: 2
#2David A. HorwitzH-Index: 50
Last. Antonio La CavaH-Index: 58
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#1Enrico MunariH-Index: 26
#2Marcella MarconiH-Index: 10
Last. Giuseppe BoginaH-Index: 22
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#1Mingya YangH-Index: 1
#2Lei WangH-Index: 12
Last. Anita SchmittH-Index: 27
view all 18 authors...
#1Katherine Young (Duke University)
#2Hakim Azfar Ali (Duke University)H-Index: 4
Last. Laurie D. Snyder (Duke University)H-Index: 27
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Long term outcomes in lung transplant are limited by the development of chronic lung allograft dysfunction (CLAD). Within the past several decades, antibody-mediated rejection (AMR) has been recognized as a risk factor for CLAD. The presence of HLA antibodies in lung transplant candidates, “sensitized patients” may predispose patients to AMR, CLAD, and higher mortality after transplant. This review will discuss issues surrounding the sensitized patient, including mechanisms of sensitization, imp...
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T cell
Immune system
Cell biology