Performance of computerized cardiotocography-based short-term variation in late-onset small-for-gestational-age fetuses and reference ranges for the late third trimester

Published on Feb 1, 2019in Archives of Gynecology and Obstetrics2.283
· DOI :10.1007/S00404-018-4966-3
Oliver Graupner5
Estimated H-index: 5
(TUM: Technische Universität München),
Javier U. Ortiz9
Estimated H-index: 9
(TUM: Technische Universität München)
+ 6 AuthorsSilvia M. Lobmaier12
Estimated H-index: 12
(TUM: Technische Universität München)
Purpose Fetal Doppler changes are well characterized in early-onset small-for-gestational-age (SGA) and fetal growth restriction (FGR) but less well characterized where the condition is late-onset. The aim of the study was to evaluate the role of computerized CTG (cCTG)-based short-term variation (STV) in late-onset SGA and FGR as an additional monitoring modality and to establish STV reference ranges in late third trimester healthy pregnancies.
📖 Papers frequently viewed together
1 Citations
11 Citations
1 Citations
#2A. Rita GaioH-Index: 1
Last. João BernardesH-Index: 28
view all 4 authors...
OBJECTIVE: To compare longitudinal trends of cardiotocographic (CTG) parameters between small-for-gestational-age (SGA) and normal fetuses, from 24 to 41 weeks of pregnancy. METHODS: A prospective cohort study was carried out in singleton pregnancies without fetal malformations. At least one CTG was performed in each of the following intervals: 24-26 weeks+6 days, 27-29 weeks+6 days, 30-32 weeks+6 days, 33-35 weeks+6 days, 36-38 weeks+6 days and ≥39 weeks. Tracings were analyzed using the Omnivi...
9 CitationsSource
#1Silvia M. LobmaierH-Index: 12
#2C PlanklH-Index: 1
Last. A Wacker-GussmannH-Index: 1
view all 8 authors...
1 CitationsSource
Objective To determine, by expert consensus, a definition for early and late fetal growth restriction (FGR) through a Delphi procedure. Method A Delphi survey was conducted among an international panel of experts on FGR. Panel members were provided with 18 literature-based parameters for defining FGR and were asked to rate the importance of these parameters for the diagnosis of both early and late FGR on a 5-point Likert scale. Parameters were described as solitary parameters (parameters that ar...
424 CitationsSource
#1Asma Khalil (St George's, University of London)H-Index: 54
#2José Morales-Roselló (St George's, University of London)H-Index: 13
Last. B. Thilaganathan (St George's, University of London)
view all 7 authors...
Objective We sought to evaluate the association between fetal cerebroplacental ratio (CPR) and intrapartum fetal compromise and admission to the neonatal unit (NNU) in term pregnancies. Study Design This was a retrospective cohort study in a single tertiary referral center over a 14-year period from 2000 through 2013. The umbilical artery pulsatility index, middle cerebral artery pulsatility index, and CPR were recorded within 2 weeks of delivery. The birthweight (BW) values were converted into ...
128 CitationsSource
#1Asma Khalil (St George's, University of London)H-Index: 54
#2José Morales-Roselló (St George's, University of London)H-Index: 13
Last. Basky Thilaganathan (St George's, University of London)H-Index: 29
view all 7 authors...
Objective Fetal cerebroplacental ratio is emerging as a better proxy than birthweight for placental insufficiency and as a marker of fetal compromise at term. The extent to which these fetal Doppler changes are related to neonatal outcomes has not been systematically assessed. The main aim of this study was to evaluate the association between estimated fetal weight percentile, cerebroplacental ratio recorded at 34 +0 –35 +6 weeks' gestation, and neonatal unit admission at term. Study Design This...
73 CitationsSource
#1Greggory R. DeVore (UCLA: University of California, Los Angeles)H-Index: 28
The cerebroplacental ratio (CPR) is emerging as an important predictor of adverse pregnancy outcome, and this has implications for the assessment of fetal well-being in fetuses diagnosed as small for gestational age (SGA) and those appropriate for gestational age close to term. Interest in this assessment tool has been rekindled because of recent reports associating an abnormal ratio with adverse perinatal events and associated postnatal neurological outcome. Fetuses with an abnormal CPR that ar...
173 CitationsSource
Summary Background No consensus exists for the best way to monitor and when to trigger delivery in mothers of babies with fetal growth restriction. We aimed to assess whether changes in the fetal ductus venosus Doppler waveform (DV) could be used as indications for delivery instead of cardiotocography short-term variation (STV). Methods In this prospective, European multicentre, unblinded, randomised study, we included women with singleton fetuses at 26–32 weeks of gestation who had very preterm...
224 CitationsSource
#1Neeta L. Vora (UNC: University of North Carolina at Chapel Hill)H-Index: 17
#2Nancy C. Chescheir (UNC: University of North Carolina at Chapel Hill)H-Index: 24
1 CitationsSource
#1F. Figueras (University of Barcelona)H-Index: 35
#2S. SavchevH-Index: 12
Last. Eduard Gratacós (University of Barcelona)H-Index: 88
view all 5 authors...
Objective To develop an integrated model with the best performing criteria for predicting adverse outcome in small-for-gestational-age (SGA) pregnancies. Methods A cohort of 509 pregnancies with a suspected SGA fetus, eligible for trial of labor, was recruited prospectively and data on perinatal outcome were recorded. A predictive model for emergency Cesarean delivery because of non-reassuring fetal status or neonatal acidosis was constructed using a decision tree analysis algorithm, with predic...
89 CitationsSource
#1Stamatina Iliodromiti (Glasgow Royal Infirmary)H-Index: 21
#2Daniel F. Mackay (Glas.: University of Glasgow)H-Index: 45
Last. Scott M. Nelson (Glasgow Royal Infirmary)H-Index: 73
view all 5 authors...
Summary Background The Apgar score has been used worldwide as an index of early neonatal condition for more than 60 years. With advances in health-care service provision, neonatal resuscitation, and infant care, its present relevance is unclear. The aim of the study was to establish the strength of the relation between Apgar score at 5 min and the risk of neonatal and infant mortality, subdivided by specific causes. Methods We linked routine discharge and mortality data for all births in Scotlan...
132 CitationsSource
Cited By4
#1Marco La Verde (Seconda Università degli Studi di Napoli)H-Index: 3
#2Gaetano Riemma (Seconda Università degli Studi di Napoli)H-Index: 7
Last. Pasquale De Franciscis (Seconda Università degli Studi di Napoli)H-Index: 20
view all 10 authors...
To estimate the correlation between the maternal perception of Braxton-Hicks contractions (BHC) and foetal wellbeing throughout antepartum computerised cardiotocography (cCTG) parameters, we performed a prospective observational study between April 2019 and March 2020. Non-labouring women with a term pregnancy were recruited. We collected data regarding maternal perception of BHC in the last two weeks before delivery. For each patient, an external computerised cardiotocography (cCTG) was registe...
#1Bronacha Mylrea-Foley (Imperial College London)
#2Christoph Lees (Imperial College London)H-Index: 55
Late fetal growth restriction (FGR) poses its own challenges in respect of diagnosis, surveillance and delivery timing. Perinatal morbidity is relatively rare, and mortality extremely unusual, but given that late FGR is much more frequent than early FGR, the burden on neonatal services must not be underestimated. Doppler findings are more subtle than in early FGR, and growth rate rather than absolute fetal size may be important in defining the condition. Though umbilical artery Doppler changes f...
#1Oliver Graupner (TUM: Technische Universität München)H-Index: 5
#2Anne Karge (TUM: Technische Universität München)H-Index: 4
Last. Bettina Kuschel (TUM: Technische Universität München)H-Index: 6
view all 11 authors...
Purpose The sFlt-1 (soluble fms-like tyrosine kinase-1)/PlGF (placental growth factor) ratio and uterine artery Doppler have shown to be helpful in the diagnosis of pre-eclampsia (PE). The predictive value of the cerebroplacental ratio (CPR) regarding adverse perinatal outcome (APO) in low-risk pregnancies is intensively discussed. We evaluated the extent to which sFlt-1/PlGF ratio and feto-maternal Doppler may be useful in predicting APO in singleton pregnancies complicated by late-onset PE and...
7 CitationsSource
Objective To evaluate the association of short-term variation (STV) and Doppler parameters with adverse perinatal outcome in small-for-gestational-age (SGA) fetuses at term.
1 CitationsSource