Original paper
Suzuki-Miyaura cross-coupling reaction of monohalopyridines and l-aspartic acid derivative
Abstract
Suzuki-Miyaura cross-coupling reaction of halogenated pyridines and a borated l-aspartic acid derivative was conducted. The reactivity of chloro-, bromo-, and iodo-pyridines with substituents at the C2, C3, and C4 positions was investigated. Electron density of halogenated pyridines was also estimated by density functional theory (DFT) calculations. The order of experimental yield of halogen substituents was Br > I >> Cl and C3 > C2, C4 whereas...
Paper Details
Title
Suzuki-Miyaura cross-coupling reaction of monohalopyridines and l-aspartic acid derivative
Published Date
Dec 1, 2018
Journal
Volume
59
Issue
52
Pages
4602 - 4605
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Notes
History