The Key Role of TNF-TNFR2 Interactions in the Modulation of Allergic Inflammation: A Review
Abstract
Tumor necrosis factor-alpha (TNF) is a pleiotropic cytokine, which is thought to play a major role in the pathogenesis of inflammatory diseases, including allergy. TNF is produced at the early stage of allergen sensitization, and then continues to promote the inflammation cascade in the effector phase of allergic reactions. Consequently, anti-TNF treatment has been proposed as a potential therapeutic option. However, recent studies reveal...
Paper Details
Title
The Key Role of TNF-TNFR2 Interactions in the Modulation of Allergic Inflammation: A Review
Published Date
Nov 9, 2018
Journal
Volume
9
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