Original paper
Stromal protein βig-h3 reprogrammes tumour microenvironment in pancreatic cancer
Abstract
Pancreatic cancer is associated with an abundant stromal reaction leading to immune escape and tumour growth. This massive stroma drives the immune escape in the tumour. We aimed to study the impact of βig-h3 stromal protein in the modulation of the antitumoural immune response in pancreatic cancer.We performed studies with p48-Cre;KrasG12D, pdx1-Cre;KrasG12D;Ink4a/Arffl/fl, pdx1-Cre;KrasG12D; p53R172H mice and tumour tissues from patients with...
Paper Details
Title
Stromal protein βig-h3 reprogrammes tumour microenvironment in pancreatic cancer
Published Date
Nov 10, 2018
Journal
Volume
68
Issue
4
Pages
693 - 707
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Notes
History