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#1Helen SteedH-Index: 25
#2Umair KamranH-Index: 1
Last. Nigel TrudgillH-Index: 25
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This is an accepted manuscript of an abstract presented at BSG Annual Meeting 2021, published by BMJ/British Society of Gastroenterology in Gut (in press). The accepted version of the publication may differ from the final published version.
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#1Helen SteedH-Index: 25
#2Umair KamranH-Index: 1
view all 5 authors...
This is an accepted manuscript of an abstract presented at BSG Annual Meeting 2021, published by BMJ/British Society of Gastroenterology in Gut (in press). The accepted version of the publication may differ from the final published version.
Source
#1Marta B. Afonso (University of Lisbon)H-Index: 11
#2Pedro Luiz Coelho Rodrigues (University of Lisbon)H-Index: 24
Last. Cecília M. P. Rodrigues (University of Lisbon)H-Index: 71
view all 18 authors...
Objective Receptor-interacting protein kinase 3 (RIPK3) is a key player in necroptosis execution and an emerging metabolic regulator, whose contribution to non-alcoholic fatty liver disease (NAFLD) is controversial. We aimed to clarify the impact of RIPK3 signalling in the pathogenesis of human and experimental NAFLD. Design RIPK3 levels were evaluated in two large independent cohorts of patients with biopsy proven NAFLD diagnosis and correlated with clinical and biochemical parameters. Wild-typ...
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#1Andrea C MasiH-Index: 2
Last. Christopher J. StewartH-Index: 26
view all 12 authors...
Objective Necrotising enterocolitis (NEC) is a devastating intestinal disease primarily affecting preterm infants. The underlying mechanisms are poorly understood: mother’s own breast milk (MOM) is protective, possibly relating to human milk oligosaccharide (HMO) and infant gut microbiome interplay. We investigated the interaction between HMO profiles and infant gut microbiome development and its association with NEC. Design We performed HMO profiling of MOM in a large cohort of infants with NEC...
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#1Zillah Cargill (University of Cambridge)H-Index: 2
#2Tamsin Cargill (University of Oxford)H-Index: 15
Last. Jonathan Marshall (University of Oxford)H-Index: 1
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An 87-year-old woman presented with a 2-day history of melaena and symptomatic anaemia. Medical history included idiopathic hyperthyroidism, a gastric ulcer and diverticular disease. On arrival, vital signs were stable apart from a tachycardia (107 bpm). Her initial haemoglobin was 48 g/L and urea 32.7 mmol/L. A large anterior neck mass was observed on examination. At endoscopy, this abnormality was identified in the upper oesophagus (figure 1). Minimal gastritis and a normal duodenum were also ...
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#1Ming-Lung Yu (KMU: Kaohsiung Medical University)H-Index: 62
#2Chung-Feng Huang (KMU: Kaohsiung Medical University)H-Index: 26
Last. Sheng-Wen Niu (KMU: Kaohsiung Medical University)H-Index: 7
view all 23 authors...
Objective HCV prevails in uremic haemodialysis patients. The current study aimed to achieve HCV microelimination in haemodialysis centres through a comprehensive outreach programme. Design The ERASE-C Campaign is an outreach programme for the screening, diagnosis and group treatment of HCV encompassing 2323 uremic patients and 353 medical staff members from 18 haemodialysis centres. HCV-viremic subjects were linked to care for directly acting antiviral therapy or received on-site sofosbuvir/velp...
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#1Valentina SvicherH-Index: 28
#2Romina SalpiniH-Index: 19
Last. Patrick T.F. KennedyH-Index: 31
view all 15 authors...
Objective The involvement of HBV DNA integration in promoting hepatocarcinogenesis and the extent to which the intrahepatic HBV reservoir modulates liver disease progression remains poorly understood. We examined the intrahepatic HBV reservoir, the occurrence of HBV DNA integration and its impact on the hepatocyte transcriptome in hepatitis B ‘e’ antigen (HBeAg)-negative chronic hepatitis B (CHB). Design Liver tissue from 84 HBeAg-negative patients with CHB with low (n=12), moderate (n=25) and h...
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#1Daniel Sk Liu (Imperial College London)
#2Adam E Frampton (Imperial College London)H-Index: 33
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#1Antonio Bertoletti (NUS: National University of Singapore)H-Index: 79
#2Carolina BoniH-Index: 29
HBV is a DNA virus that coevolved with humans.1 Different from many other viruses that are detected only after amplification of their genetic material, HBV is characterised by the production of a progeny of infectious virions, but also of high concentrations (5–10 μg/mL) of viral proteins. These proteins are ‘byproducts’ of the synthesis of the proteins coded by HBV core and HBV pre-S1, pre-S2 and S genes, the building blocks of the nucleocapsid (the internal part of the virus containing HBV–DNA...
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#1Emad Mansoor (University Hospitals of Cleveland)H-Index: 11
#2Muhammed Mustafa Alikhan (University Hospitals of Cleveland)
Last. Alberto Rubio-Tapia (Cleveland Clinic)H-Index: 4
view all 6 authors...
We read with interest the work by Belli et al 1 regarding outcomes of COVID-19 in liver transplant candidates. The authors concluded that liver transplant candidates were at risk of early death, especially those with decompensated cirrhosis and model for end-stage liver disease score≥15. Similarly, patients with coeliac disease (CD) are a population of interest in regards to clinical outcomes after a diagnosis of COVID-19. Although the evidence of an impact of other chronic disorders on the outc...
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