Response of intestinal metabolome to polysaccharides from mycelia of Ganoderma lucidum

Polysaccharides from the mycelia of Ganoderma lucidum (GLP) can improve intestinal barrier function, regulate intestinal immunity and modulate intestinal microbiota. In the present study, GLP was given via oral administration to rats (100 mg/kg body weight, 21 days) to investigate the metabolomic profiling of caecal contents induced by GLP. Gas chromatography-time of light/mass spectrometry (GC-TOF/MS) was performed to identify the metabolites,...