In vivo visualization of age-related differences in the locus coeruleus
Abstract
The locus coeruleus (LC), the major origin of noradrenergic modulation of the central nervous system, may play an important role in neuropsychiatric disorders including Parkinson's disease and Alzheimer's disease. The pattern of age-related change of the LC across the life span is unclear. We obtained normalized, mean LC signal intensity values, that is, contrast ratios (CRs), from magnetization transfer–weighted images to investigate the...
Paper Details
Title
In vivo visualization of age-related differences in the locus coeruleus
Published Date
Feb 1, 2019
Journal
Volume
74
Pages
101 - 111
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