Development of a Method to Characterize the Effects of Radiation on Growth and Morphology of Organoids in 3D Culture

Organoids are a powerful tool to monitor the temporal effects of radiation in vitro , offering distinct advantages over traditional 2D cell culture methods. In addition to growing into 3D structures that more closely model physiologic cellular architecture, individual organoids embedded in gel matrices can be tracked over time, making it possible to study the temporal effects of radiation on growth in clonal cell populations. However,...