Saponin isolates from cucumber (Cucumis sativus L.) fruit mesocarp and their activity as pancreatic lipase inhibitor

Obesity can be tackled by anti-obesity drugs, like Orlistat, that inhibit digestive enzymes such as pancreatic lipase. The drug has limited availability and is quite expensive. Earlier studies have shown that mesocarp cucumber (Cucumis sativus L.) juice is capable of inhibiting pancreatic lipase and some types of saponins from other plants are also inhibitors for pancreatic lipase. This study seeks to isolate the saponin class from cucumber...