Persistence of radiation-induced aberrations in patients after radiotherapy with C-ions and IMRT

Background and purposeChromosomal aberrations in peripheral blood lymphocytes are a biomarker for radiation exposure and are associated with an increased risk for malignancies. To determine the long-term cytogenetic effect of radiotherapy, we analyzed the persistence of different aberration types up to 2.5 years after the treatment.Materials and methodsCytogenetic damage was analyzed in lymphocytes from 14 patients that had undergone C-ion boost...