Effect of platelet‐rich plasma on proliferation and migration in human dermal fibroblasts

Summary Background Platelet‐rich plasma (PRP) is a blood fraction that contains high concentrations of several growth factors. PRP has been recently used in skin wound healing and rejuvenation. However, the precise molecular mechanisms underlying PRP‐induced wound healing are unknown. Aims This study aimed to evaluate the effects of PRP on extracellular matrix remodeling, which requires the activation of dermal fibroblasts. Methods Cell...