Incidental histological diagnosis of small pancreatic neuroendocrine tumors: are we underestimating their incidence?

Background: The annual incidence of pancreatic neuroendocrine tumors (PanNET) has been estimated to be around 0.8/100,000 inhabitants. Aim of the study was to determine the frequency of incidental histological diagnosis of PanNET during pancreatic specimen evaluation for other neoplasms. Method: We retrospectively reviewed 1023 histopathological examinations of pancreatic specimens performed by three different pathologists in 3 high-volume...