Stefano Partelli
Vita-Salute San Raffaele University
Internal medicineRadiologySurgeryPathologyOncologyResectionRetrospective cohort studySurvival rateCarcinomaPancreatectomyPancreasPancreaticoduodenectomyNeuroendocrine tumorsDiseasePancreatic cancerPancreatic fistulaAdenocarcinomaIn patientPerioperativeGeneral surgeryMedicineGastroenterology
266Publications
43H-index
4,831Citations
Publications 264
Newest
#1Irvin M. Modlin (Yale University)H-Index: 81
#2Mark KiddH-Index: 66
Last. Alexandra KitzH-Index: 2
view all 17 authors...
Introduction Surgery is the only cure for neuroendocrine tumors (NETs), with R0 resection being critical for successful tumor removal. Early detection of residual disease is key for optimal management, but both imaging and current biomarkers are ineffective post-surgery. NETest, a multigene blood biomarker, identifies NETs with >90% accuracy. We hypothesized that surgery would decrease NETest levels and that elevated scores post-surgery would predict recurrence. Methods This was a multicenter ev...
3 CitationsSource
#1Stefano Partelli (UniSR: Vita-Salute San Raffaele University)H-Index: 43
#2Valentina Andreasi (UniSR: Vita-Salute San Raffaele University)H-Index: 8
Last. Massimo Falconi (UniSR: Vita-Salute San Raffaele University)H-Index: 105
view all 12 authors...
Abstract Background A fatty infiltration of the pancreas has been traditionally regarded as the main histological risk factor for postoperative pancreatic fistula, whereas the role of the secreting acinar compartment has been poorly investigated. The aim of this study was to evaluate the role of acinar content at pancreatic resection margin in the development of clinically relevant postoperative pancreatic fistula and clinically relevant postoperative acute pancreatitis after pancreaticoduodenec...
Source
#1Fabio Casciani (UPenn: University of Pennsylvania)H-Index: 2
#2Maxwell T. Trudeau (UPenn: University of Pennsylvania)H-Index: 3
Last. Ronald R. SalemH-Index: 29
view all 56 authors...
Abstract Background The association between intraoperative estimated blood loss and outcomes after pancreatoduodenectomy has, thus far, been rarely explored. Methods In total, 7,706 pancreatoduodenectomies performed at 18 international institutions composing the Pancreas Fistula Study Group were examined (2003–2020). High estimated blood loss (>700 mL) was defined as twice the median. Propensity score matching (1:1 exact-match) was employed to adjust for variables associated with high estimated ...
Source
#1Nicolò PecorelliH-Index: 20
#2Michele MazzaH-Index: 4
Last. Massimo FalconiH-Index: 105
view all 10 authors...
Abstract Background In bowel surgery, adherence to enhanced recovery program (ERP) has been associated with improved recovery. The objective of this study was to evaluate the impact of adherence to ERP elements on outcomes, and identify factors associated with successful recovery following distal pancreatectomy (DP). Methods Data for 376 patients who underwent DP managed within an ERP including 16 perioperative elements were reviewed. Primary endpoint was successful recovery, a composite outcome...
Source
#1Stefano CrippaH-Index: 60
#2G. Belfiori (UniSR: Vita-Salute San Raffaele University)H-Index: 6
Last. Massimo FalconiH-Index: 105
view all 10 authors...
Abstract Background Current treatment of potentially resectable pancreatic ductal adenocarcinoma (PDAC) includes pancreatic resection followed by adjuvant therapy. Aim of this study is to identify factors that are related with overall and early recurrence after pancreatectomy for PDAC. Methods Retrospective analysis of patients with histologically confirmed PDAC who underwent pancreatectomy between September 2009 and December 2014. Early relapse was defined as recurrence within 12 months after s...
Source
#1Stefano CrippaH-Index: 60
Last. Marco Del Chiaro (Anschutz Medical Campus)H-Index: 31
view all 14 authors...
Abstract Background 2017 International and 2018 European guidelines are the most recent guidelines for intraductal papillary mucinous neoplasms management. Aim to evaluate the diagnostic accuracy of these guidelines in identifying malignant IPMN. Methods data from resected patients with IPMN were collected in two referral centers. Features of risk associated to cancerous degeneration described in International and European guidelines were retrospectively applied. Sensitivity, specificity, positi...
Source
#1Carolina Bezzi (UniSR: Vita-Salute San Raffaele University)H-Index: 1
#2Paola Mapelli (UniSR: Vita-Salute San Raffaele University)H-Index: 12
Last. Maria Picchio (UniSR: Vita-Salute San Raffaele University)H-Index: 59
view all 11 authors...
PURPOSE To present the state-of-art of radiomics in the context of pancreatic neuroendocrine tumors (PanNETs), with a focus on the methodological and technical approaches used, to support the search of guidelines for optimal applications. Furthermore, an up-to-date overview of the current clinical applications of radiomics in the field of PanNETs is provided. METHODS Original articles were searched on PubMed and Science Direct with specific keywords. Evaluations of the selected studies have been...
Source
#1Stefano PartelliH-Index: 43
#2Claudio RicciH-Index: 28
Last. Massimo FalconiH-Index: 105
view all 10 authors...
Abstract Background The cost-effectiveness of minimally invasive distal pancreatectomy (MIDP) is still a matter of debate. This study compares the cost-effectiveness of open (ODP), laparoscopic (LDP) and robotic distal pancreatectomy (RDP). Methods Pubmed, Web of Science and Cochrane Library databases were searched. Studies comparing cost-effectiveness of ODP and MIDP were included. Results A total of 1052 titles were screened and 16 articles were included in the study, 2431 patients in total. L...
Source
#1Domenico Tamburrino (UniSR: Vita-Salute San Raffaele University)H-Index: 16
#2Giovanni Guarneri (UniSR: Vita-Salute San Raffaele University)H-Index: 4
Last. Massimo Falconi (UniSR: Vita-Salute San Raffaele University)H-Index: 105
view all 8 authors...
Pancreatic ductal adenocarcinoma (PDAC) is currently the fourth leading cause of cancer-related death in the USA. A wealth of evidence has demonstrated the chemopreventive activity of aspirin, statins, and metformin against PDAC. The aim of this study is to investigate the effect of aspirin, statins, and metformin on disease-free survival (DFS) and disease-specific survival (DSS) in a large population of PDAC patients undergoing pancreatic resection. All patients who underwent pancreatic resecti...
1 CitationsSource
#1Fabio Casciani (UPenn: University of Pennsylvania)H-Index: 2
#2Maxwell T. Trudeau (UPenn: University of Pennsylvania)H-Index: 3
Last. John W. KunstmanH-Index: 18
view all 55 authors...
Abstract Background Pancreatoduodenectomies at high risk for clinically relevant pancreatic fistula are uncommon, yet intimidating, situations. In such scenarios, the impact of individual surgeon experience on outcomes is poorly understood. Methods The fistula risk score was applied to identify high-risk patients (fistula risk score 7–10) from 7,706 pancreatoduodenectomies performed at 18 international institutions (2003–2020). For each case, surgeon pancreatoduodenectomy career volume and years...
2 CitationsSource