Suppressing inflammation and enhancing osteogenesis using novel CS‐EC@Ca microcapsules

The aim of this study was to investigate the suppression of inflammation and enhancement of osteogenesis using chitosan‐coated calcium hydroxide‐loaded microcapsules (CS‐EC@Ca microcapsules) in vivo . Circular defects were created in the mandibular bones of rabbits and filled with Ca(OH) 2 , Bio‐oss, or CS‐EC@Ca microcapsules, and rabbits without drug implantation served as the controls. Lipopolysaccharides were injected in situ daily in all...