Original paper
PEG-4MAL hydrogels for human organoid generation, culture, and in vivo delivery
Abstract
In vitro differentiation of human pluripotent stem cell (hPSC)-derived organoids (HOs) facilitates the production of multicellular three-dimensional structures analogous to native human tissues. Most current methods for the generation of HOs rely on Matrigel, a poorly defined basement membrane derivative secreted by Engelbreth–Holm–Swarm mouse sarcoma cells, limiting the potential use of HOs for regenerative medicine applications. Here, we...
Paper Details
Title
PEG-4MAL hydrogels for human organoid generation, culture, and in vivo delivery
Published Date
Sep 1, 2018
Journal
Volume
13
Issue
9
Pages
2102 - 2119