The Structure and Dynamics of C. elegans Tubulin Reveals the Mechanistic Basis of Microtubule Growth

Microtubule polymerization involves complex structural transitions that are not fully understood. Chaaban et al. study microtubules from the nematode C. elegans, which have unique structures and dynamics in cells. They uncover a key limiting step in microtubule polymerization that involves the structuring of tubulin-tubulin interacting...