NOTCH3 expression is linked to breast cancer seeding and distant metastasis
Abstract
Development of distant metastases involves a complex multistep biological process termed the invasion-metastasis cascade, which includes dissemination of cancer cells from the primary tumor to secondary organs. NOTCH developmental signaling plays a critical role in promoting epithelial-to-mesenchymal transition, tumor stemness, and metastasis. Although all four NOTCH receptors show oncogenic properties, the unique role of each of these receptors...
Paper Details
Title
NOTCH3 expression is linked to breast cancer seeding and distant metastasis
Published Date
Sep 4, 2018
Journal
Volume
20
Issue
1
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