In vivo monitoring of the TR4 anti-Notch fusion protein: an imaging approach.
Volume: 34, Issue: 15_suppl, Pages: e23186 - e23186
Published: May 20, 2016
Abstract
e23186 Background: The Notch pathway has been associated with cancer and is implicated in tumorigenesis and regulation of cell fate. This pathway is an attractive target for the development of novel anti-Notch cancer therapeutics. We have generated a novel fusion protein TR4 that inhibits Notch at transcriptional level and can reduce tumor growth Methods: TR4 consists of the truncated Mastermind (MAML) peptide that inhibits Notch and the cell...
Paper Details
Title
In vivo monitoring of the TR4 anti-Notch fusion protein: an imaging approach.
Published Date
May 20, 2016
Journal
Volume
34
Issue
15_suppl
Pages
e23186 - e23186
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