Reactive oxygen species, aging and articular cartilage homeostasis

Volume: 132, Pages: 73 - 82
Published: Feb 1, 2019
Abstract
Chondrocytes are responsible for the maintenance of the articular cartilage. A loss of homeostasis in cartilage contributes to the development of osteoarthritis (OA) when the synthetic capacity of chondrocytes is overwhelmed by processes that promote matrix degradation. There is evidence for an age-related imbalance in reactive oxygen species (ROS) production relative to the anti-oxidant capacity of chondrocytes that plays a role in cartilage...
Paper Details
Title
Reactive oxygen species, aging and articular cartilage homeostasis
Published Date
Feb 1, 2019
Volume
132
Pages
73 - 82
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