Reducing inter- and intra-planner variability in radiotherapy plan output with a commercial knowledge-based planning solution

Purpose This study measured to which extent RapidPlan can drive a reduction of the human-caused variability in prostate cancer treatment planning. Methods Seventy clinical prostate plans were used to train a RapidPlan model. Seven planners, with different levels of planning experience, were asked to plan a VMAT treatment for fifteen prostate cancer patients with and without RapidPlan assistance. The plans were compared on the basis of target...