c-MET Overexpression as a Poor Predictor of MET Amplifications or Exon 14 Mutations in Lung Sarcomatoid Carcinomas

Volume: 13, Issue: 12, Pages: 1962 - 1967
Published: Dec 1, 2018
Abstract
IntroductionMNNG HOS transforming gene (MET) abnormalities such as amplification and exon 14 mutations may be responsive to targeted therapies. They are prevalent in lung sarcomatoid carcinomas (LSCs) and must be diagnosed as efficiently as possible. Hypothetically, c-MET overexpression by immunohistochemistry (IHC) may prove effective as a screening test for MET abnormalities.MethodsTissue samples were obtained from consecutive patients with a...
Paper Details
Title
c-MET Overexpression as a Poor Predictor of MET Amplifications or Exon 14 Mutations in Lung Sarcomatoid Carcinomas
Published Date
Dec 1, 2018
Volume
13
Issue
12
Pages
1962 - 1967
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