Single-cell mapping of the thymic stroma identifies IL-25-producing tuft epithelial cells

Nature64.80
Volume: 559, Issue: 7715, Pages: 622 - 626
Published: Jul 1, 2018
Abstract
T cell development and selection are coordinated in the thymus by a specialized niche of diverse stromal populations1-3. Although much progress has been made over the years in identifying the functions of the different cell types of the thymic stromal compartment, there is no comprehensive characterization of their diversity and heterogeneity. Here we combined massively parallel single-cell RNA-sequencing4,5, spatial mapping, chromatin profiling...
Paper Details
Title
Single-cell mapping of the thymic stroma identifies IL-25-producing tuft epithelial cells
Published Date
Jul 1, 2018
Journal
Volume
559
Issue
7715
Pages
622 - 626
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