Original paper
Effects of CDX2 on prognosis and chemotherapy responsiveness in mismatch repair-deficient colorectal cancer
Abstract
Caudal-related homeobox transcription factor 2 (CDX2) is an intestine-specific transcription factor implicated in tumour differentiation, proliferation, cell adhesion and migration. Negative CDX2 status (CDX2-) is associated with worse prognosis in colorectal cancer and may identify high-risk stage II disease that benefits from adjuvant chemotherapy. This observational study investigated whether CDX2- is associated with prognosis or response to...
Paper Details
Title
Effects of CDX2 on prognosis and chemotherapy responsiveness in mismatch repair-deficient colorectal cancer
Published Date
Jul 24, 2018
Journal
Volume
2
Issue
6
Pages
456 - 463
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Notes
History