Real-time detection of prostate-specific antigens using a highly reliable fiber-optic localized surface plasmon resonance sensor combined with micro fluidic channel

Conventional assays using fiber-optic localized surface plasmon resonance (FO LSPR) sensors involve soaking the sensor in solution, which exposes the sensor to air during measurement. Although the exposure time is short, for a small sensor surface area, this can result in drying of biomolecules and rearrangement of nanoparticles caused by the surface tension. To minimize the resulting errors, FO LSPR sensor was combined with a micro fluidic...