Identification of a new subset of lymph node stromal cells involved in regulating plasma cell homeostasis

Abstract
Antibody-secreting plasma cells (PCs) arise rapidly during adaptive immunity to control infections. The early PCs are retained within the reactive lymphoid organ where their localization and homeostasis rely on extrinsic factors, presumably produced by local niche cells. While myeloid cells have been proposed to form those niches, the contribution by colocalizing stromal cells has remained unclear. Here, we characterized a subset of fibroblastic...
Paper Details
Title
Identification of a new subset of lymph node stromal cells involved in regulating plasma cell homeostasis
Published Date
Jul 2, 2018
Volume
115
Issue
29
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