Neurocognitive

Physical therapy

Athletes

Injury prevention

Poison control

Internal medicine

Asymptomatic

Concussion

Medicine

Cognition

Emergency medicine

Blood sampling

Psychiatry

Journal of neurosurgery

This prospective observational cohort study of high-school football athletes was performed to determine if high-acceleration head impacts (HHIs) that do not result in clinically diagnosed concussion still lead to increases in serum levels of biomarkers indicating traumatic brain injury (TBI) in asymptomatic athletes and to determine the longitudinal profile of these biomarkers over the course of the football season.

Elevated markers of brain injury as a result of clinically asymptomatic high-acceleration head impacts in high-school football athletes