Salinomycin induces apoptosis and differentiation in human acute promyelocytic leukemia cells
Abstract
At present, acute promyelocytic leukemia (APL) is the most curable form of acute myeloid leukemia and can be treated using all-trans retinoic acid and arsenic trioxide. However, the current treatment of APL is associated with some issues such as drug toxicity, resistance and relapse. Therefore, other strategies are necessary for APL treatment. In the present study, we investigated the effects of salinomycin (SAL) on APL cell lines NB4 and HL-60...
Paper Details
Title
Salinomycin induces apoptosis and differentiation in human acute promyelocytic leukemia cells
Published Date
Jun 20, 2018
Journal
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