3D genome and its disorganization in diseases

Volume: 34, Issue: 5, Pages: 351 - 365
Published: May 23, 2018
Abstract
The chromosomes in eukaryotic cells are highly folded and organized to form dynamic three-dimensional (3D) structures. In recent years, many technologies including chromosome conformation capture (3C) and 3C-based technologies (Hi-C, ChIA-PET) have been developed to investigate the 3D structure of chromosomes. These technologies are enabling research on how gene regulatory events are affected by the 3D genome structure, which is increasingly...
Paper Details
Title
3D genome and its disorganization in diseases
Published Date
May 23, 2018
Volume
34
Issue
5
Pages
351 - 365
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