A new coumarin-secoiridoid diglucoside, named Isofraxisecoside, was isolated from the stem bark of Fraxinus xanthoxyloides (G. Don) Wall. ex A. DC. along with nine known compounds. The stru...
#2Xiao-Dan Ren(Tianjin University of Science and Technology)H-Index: 5
Last. Wu Lei(Tianjin University of Science and Technology)H-Index: 6
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A new natural compound, esculetin-5-O-β-D-glucopyranoside (1), along with two known flavonoids, quercetin (2) and kaempferol-3-β-D-glucopyranoside (3), was purified from the heartwood of Fraxinus velutina. Their chemical structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR, and MS techniques.
One new, namely 6-methoxykaempferol 3-O-[β-apiofuranosyl(l-->2)]-f-glucopyranosyl(l->6)-fl-glucopyranoside (2), and two known flavonoid glycosides, spinacetin 3-O-[β-apiofuranosyl(1-->2)]-β-glucopyranosyl(1-->6)-β-glucopyranoside (1) and spinacetin 3-O-gentiobioside (3), were isolated from the roots of Chenopodium bonus-henricus L. Their structures were determined by means of spectroscopic methods (ID, 2D NMR, UV, IR) and HR-ESI-MS. Radical scavenging and anti-oxidant activities of 1 and 3 were ...
In this paper, a chromatographic method for isolation and purification of coumarin compounds from Cortex fraxinus was established by using Superose 12 as the separation media for the first time. The conditions for separation were optimized. Four kinds of coumarin compounds including aesuletin, aesculin, fraxetin and fraxin were obtained. The purity of these compounds were 98.5, 99.1, 97.9 and 97.3%, respectively, which were determined by HPLC area normalization method. The chemical structures of...
Last. Surk-Sik Moon(KNU: Kongju National University)H-Index: 25
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Phytochemical investigation of the methanolic extract of Diospyros kaki leaves led to the isolation of osmanthuside H (1) and a new phenol glycoside, named gamnamoside [4-(3-hydroxypropyl)-2-methoxyphenol -D-apiofuranosyl( 1 6)-D-glucopyranoside] (2) along with (-) catechin (3) through a series of reversed phase column chromatography and preparative C18 HPLC. The structures of the isolates were determined by spectroscopic methods including IR, UV, HRTOFMS, and 2D NMR. Compounds 1, 2, and 3, show...
Stelleropsis genus belongs to T hymelaeaceae and h as two species in Iran of which S. iranica Pobed. sub sp. Iranica Bonge (aerial parts) were collected from the N orth-East of Iran and extracted with AcOEt and M eOH, consequently. The main phenolic compounds were isolated by different chromatography methods and the structures identified by spectroscopic methods (1H-NMR, 13C-NMR, HMBC, HMQC, H-H COSY, EI-MS) as syringin (1), gengkwanin 5-O-â-D-primeveroside (Yuankanin) ( 2), syr ingaresinol ( 3)...
#1Eva Wallander(TNC: The Nature Conservancy)H-Index: 1
Phylogenetic relationships among 40 of the 43 recognized species of Fraxinus L. (Oleaceae) were estimated on the basis of 106 nuclear ribosomal ITS sequences. ITS trees resulting from maximum likelihood (ML), maximum parsimony (MP) and Bayesian inference (BI) are congruent and identify six distinct lineages. These clades allow establishing sections with high molecular and morphological support. The basal resolution generally has low ML bootstrap and MP jackknife support, but the Bayesian posteri...
#1Kai Xiao(CAS: Chinese Academy of Sciences)H-Index: 1
#2Qing-Hong Song(CAS: Chinese Academy of Sciences)H-Index: 1
Last. Li-Jiang Xuan(CAS: Chinese Academy of Sciences)H-Index: 19
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Chemical studies on the roots of Fraxinus rhynchophylla led to the isolation of fraxisecoside (1), a novel coumarin–secoiridoid hybrid glycoside, namely, fraxetin-8-O-[11′-methyl-oleosidyl-(7′ → 6″)]-β-d-glucopyranoside and 14 known compounds. Their structures were elucidated based on chemical evidence and spectroscopic analysis, including extensive 2D NMR methods. Compound 2 was first isolated as a pure compound. Compound 1 exhibited moderate PTP1B inhibition activity. Compounds 1 and 2 showed ...
One-pot reactions of aldoses with L-cysteine methyl ester and o-tolyl isothiocyanate yielded methyl 2-(polyhydroxyalkyl)-3-(o-tolylthiocarbamoyl)-thiazolidine-4(R)-carboxylates. Direct HPLC analysis of the reaction mixture and UV detection at 250 nm discriminated D- and L-enantiomers of aldoses. The reaction was applied to the determination of absolute configuration the sugar residues of an aroma precursor.
#1Ivanka Kostova(BAS: Bulgarian Academy of Sciences)H-Index: 16
#2Tanya Iossifova(BAS: Bulgarian Academy of Sciences)H-Index: 10
Abstract A wide range of chemical components including coumarins, secoiridoids, phenylethanoids, flavonoids, and lignans has been isolated from Fraxinus species. Extracts and metabolites have been found to possess antiinflammatory, immunomodulatory, antimicrobial, antioxidative, skin regenerating, photodynamic damage prevention, liverprotecting, diuretic and antiallergic activities. Some species find application in contemporary medicine. In the present review the literature data on the phytochem...
Structural examination of the metabolic pool of the aerial parts of Pelargonium sidoides DC has led to the isolation of two new metabolites, 4-allyl-2,5-dimethoxyphenol-1-β-D-gluco-pyranoside and 6,7-dihydroxycoumarin-8-sulfate, along with a series of uncommon compounds including (2R,3R)-(+)-dihydroquercetin-3-β-glucopyranoside, (2R,3R)-(+)-dihydrokaempferol-3-β-glucopyranoside, fraxetin-7-β-glucopyranoside, 7-methoxycoumarin-6-β-glucopyranoside, umckalin, orientin-2"-gallate, and isoorientin-2"...
AbstractA new monoterpene glycoside named as pedivertoside D (1), together with 13 known compounds (2–14, resp.) were isolated from the whole plant of Pedicularis verticillata L. The new compound w...
#2Xu-Jie Qin(CAS: Chinese Academy of Sciences)H-Index: 19
Last. Ying-Jun Zhang(CAS: Chinese Academy of Sciences)H-Index: 28
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Abstract Ten previously undescribed glycosides, carissaedulosides A-J (1-10) referring to six apiosylated phenylpropanoids (1-6), one coumarin-secoiridoid hybrid (7), and three furofuran lignans (8-10) were isolated from the root barks of Carissa edulis, together with 13 known analogues (11-23). Their structures were elucidated by spectroscopic analysis, ECD computational methods, and chemical derivations for configurations of sugar moieties. The new lignan bisdesmoside, 10, exhibited significan...
AbstractA new isocoumarin (1) named fraxicoumarin was isolated from the bark of Fraxinus chinensis subsp. rhynchophylla along with three known compounds (2–4). The structure of the new compound was...
Last. Xiumei Gao(Tianjin University of Traditional Chinese Medicine)H-Index: 34
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Abstract In the quest to search and discover bioactive compounds from nature, terpenoids have emerged as one of the most interesting and researched classes of compounds. Secoiridoid, a type of the terpenoid, has also been extensively studied, especially their chemical structures and pharmacological effects. Oleaceae is a family of woody dicotyledonous plants with broad economic and medicinal values. This family contains a large number of flavonoids, monoterpenoids, iridoids, secoiridoids and phe...
