Natural Product Research
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#1Mengnan Zeng (Henan University)H-Index: 6
#2Man Qi (Henan University)H-Index: 3
Last. Weisheng Feng (Henan University)H-Index: 9
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A new flavonoid, (2'''E,6'''S)-4''-(6-hydroxy-2,6-dimethylocta-2,7-dienoyl)-vitexin (1), and five known compounds (2-6) were isolated from the thorn of Gleditsia sinensis Lam. Their structures were determined by comprehensive and comparative spectroscopic analysis of NMR and MS data. The absolute configuration of the new compound was deduced by analysis of the experimental and calculated 13C NMR data. The protective effects against lipopolysaccharide (LPS)-induced apoptosis in normal rat kidney ...
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#1Rafael Viteri (UC: Pontifical Catholic University of Chile)
#2Ady Giordano (UC: Pontifical Catholic University of Chile)H-Index: 5
Last. Flavia C. Zacconi (UC: Pontifical Catholic University of Chile)H-Index: 7
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Eucryphia cordifolia is a native and dominant species from the Temperate Forest in the southern region of Chile. It is a crucial melliferous species producing unifloral honey with outstanding antibacterial properties with great commercial value at international markets. A phytochemical screening was developed by colorimetric and gravimetric methods. Antioxidant activities were assessed by using 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS), and...
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#1I. E. Smirnova (RAS: Russian Academy of Sciences)H-Index: 11
#2Elena V. Tretyakova (RAS: Russian Academy of Sciences)H-Index: 8
Last. Oxana B. Kazakova (RAS: Russian Academy of Sciences)H-Index: 14
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Among abietane type semisynthetic diterpenoids, a series of quinopimaric and maleopimaric acid derivatives modified at the carboxyl and carbonyl groups, and in ring E were synthesised to obtain new compounds with antimicrobial potency against Mycobacterium tuberculosis H37Rv and key ESKAPE pathogens. It was found that compound 8 exhibited low toxicity to human embryonic kidney cell line HEK-293 (> 32 μg/mL) and showed significant bacteriostatic activity against methicillin-resistant Staphylococc...
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#1M. A. Agzamova (Academy of Sciences of Uzbekistan)H-Index: 6
#2Nilufar Z. Mamadalieva (Academy of Sciences of Uzbekistan)H-Index: 13
Last. Ludger A. Wessjohann (Leibniz Association)H-Index: 62
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Chemical investigation of the aerial parts of Astragalus lehmannianus Bunge (Leguminosae) led to the isolation and identification of a new cycloartane triterpene glycoside - lehmanniaside (2'-O-acetyl-3-β-O-D-xylopyranosyl-3β,6α,16β,24α-tetrahydroxy-20,25-epoxycycloartane). Its structure was elucidated by means of spectroscopic analysis (HR-MS, 1D and 2D NMR). Bioassays showed that lehmanniaside exhibits weak anthelmintic, antifungal, and cytotoxic activities.
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#1Zulfiqar Ali (University of Mississippi)H-Index: 28
#2Srivedavyasasri Radhakrishnan (University of Mississippi)
Last. Ikhlas A. Khan (University of Mississippi)H-Index: 71
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Salvia mellifera, native to California, Baja California, and Mexico, is a medicinal herb traditionally used to relieve pain, body aches, including chronic pain. A detailed phytochemical investigation of aerial parts of S. mellifera was accomplished to find species-specific markers and to differentiate the closely related, often (un)intentionally substituted with S. apiana. A total of 22 metabolites, including flavonoids (1-14), triterpenoids (15-18), diterpenoids (19-21), and phenylpropanoid (22...
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#1Ejike Onwudiegwu Okpala (UI: University of Ibadan)
#2Patricia A. Onocha (UI: University of Ibadan)H-Index: 8
Last. Mehreen LateefH-Index: 10
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A new iso-benzofuranone propanamide: 3-(3-oxo-1, 3-dihydroisobenzofuran-1-yl) propanamide (zenkeramide) (1) along with three known compounds: Trans-N-coumaroyltyramine (2), β-Sitosterol (3) and β-sitosterol-3-0-β-D-glucopyranoside (4) were isolated from the ethyl acetate fraction of the stem-bark of Celtis zenkeri Engl (Ulmaceae). The structure of the new compound was elucidated by extensive spectroscopic analysis. The compounds were examined for Urease Inhibitory Activity. Compounds 1 and 2 sho...
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#1Guangxin Zhou (SPU: Shenyang Pharmaceutical University)
#2Jiaming Zhao (SPU: Shenyang Pharmaceutical University)
Last. Dali Meng (SPU: Shenyang Pharmaceutical University)H-Index: 13
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The phytochemical investigation on the leaves of Psidium guajava Linn. led to the isolation and identification of 18 compounds, including six guavinoside (1-6), four flavonoids (7-10), eight triterpenoids (11-17) and one lignans (18). All chemical structures were elucidated via NMR spectroscopic methods, and further supported by comparison with literature data. Compounds 12, 14, 16 and 18 was isolated from the Myrtaceae family for the first time. The chemotaxonomic significance of these compound...
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#1Yuya Kakumu (Gidai: Gifu University)H-Index: 1
#2Thi Minh Tu Nguyen (HUST: Hanoi University of Science and Technology)H-Index: 1
Last. Tohru Mitsunaga (Gidai: Gifu University)H-Index: 19
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A new benzoic acid, 3-[2-(2-hydroxyphenyl)acetoxy]benzoic acid (1), and two new caffeoyl derivatives, methyl (3E,5Z)-di-O-caffeoylquinate (2) and dhurrin 6'-O-caffeate (3), along with 20 known compounds were isolated from the leaves of Ilex kaushue collected in Vietnam. Their structures were elucidated on the basis of 1 D and 2 D NMR spectroscopy, and high-resolution MS spectrometry. The absolute configuration of 2 and 3 was unambiguously established by comparison of experimental and calculated ...
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#1Ghada Gamal (Kafrelsheikh University)
#2Kamilia A Abo-El-Seoud (Tanta University)
Last. Ghada A. Attia (Tanta University)H-Index: 3
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A new triterpenoid named 3β,20α-dihydroxy-30-nor-olean-12-ene-23,28 dioic acid (4) along with 3β-hydroxy-23-aldehyde-lup-20(29)-ene-28-oic acid (1), 3β-hydroxy-23-aldehyde-30-nor-olean-12,20(29)-diene-28-oic acid (2), 3β-hydroxy-lup-20(29)-ene-23,28 dioic acid (3), 3β-hydroxy-lup-20(29)-ene-23,28 dioic acid-23-O-β-D-glucopyranosyl ester (5), 3-O-β-D-glucuronopyranosyl-lup-20(29)-ene-23,28 dioic acid-28-O-β-D-glucopyranosyl ester (6), 3-O-β-D-glucuronopyranosyl-lup-20(29)-ene-23-aldehyde-28-oic a...
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#1Isaac Silvère Gade (University of Poitiers)
#1Isaac Silvère Gade (University of Yaoundé I)
Last. Céline Henoumont (University of Mons)H-Index: 10
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The present work describes the isolation and anticancer activity of Tapinanthus sp. which is a hemi parasitic plant harvested on Combretum glutinosum, the host plant. Phytochemical study afforded a new flavonoid glycoside, tapinantoside (1) isolated for the first time from natural source, alongside six known compounds (2-7). Structure of compounds were elucidated by extensive spectroscopic analyses including 1 D and 2 D NMR, mass spectrometry and by comparison with literature data. The anticance...
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