Brock malignancy risk calculator for pulmonary nodules: validation outside a lung cancer screening population

Objective To assess the performance of the Brock malignancy risk model for pulmonary nodules detected in routine clinical setting. Methods In two academic centres in the Netherlands, we established a list of patients aged ≥40 years who received a chest CT scan between 2004 and 2012, resulting in 16 850 and 23 454 eligible subjects. Subsequent diagnosis of lung cancer until the end of 2014 was established through linking with the National Cancer...