Toxicokinetics, Tissue Distribution, and Excretion of Dufulin Racemate and Its R (S)-Enantiomers in Rats
Volume: 66, Issue: 28, Pages: 7265 - 7274
Published: May 21, 2018
Abstract
Dufulin is a plant antiviral agent with a novel molecular structure and has been used widely to prevent and control tobacco and rice viral diseases. In this study, an UHPLC-MS/MS method was developed for rapid determination of dufulin racemate ( rac-DFL) and its R ( S)-enantiomers in rat plasma, tissues, urine, and feces. A MALDI-MSI method was further used for visual research on tissue distribution after intragastric administration of the three...
Paper Details
Title
Toxicokinetics, Tissue Distribution, and Excretion of Dufulin Racemate and Its R (S)-Enantiomers in Rats
Published Date
May 21, 2018
Volume
66
Issue
28
Pages
7265 - 7274
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