Journal of Agricultural and Food Chemistry
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5.28
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#1Xiaoqi Wang (RU: Rutgers, The State University of New Jersey)H-Index: 3
#2Dongli Li (WYU: Wuyi University)H-Index: 12
Last. Qingrong Huang (RU: Rutgers, The State University of New Jersey)H-Index: 60
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As one of the major polymethoxyflavones in citrus peels, sinensetin (Sin) has been reported to possess numerous bioactivities. However, its detailed in vivo metabolic fate has not been uncovered yet. In the present study, the possible metabolites of Sin were synthesized, and all five mono-demethylated metabolites were successfully identified via ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) analysis in rats fed with 100 mg/(kg·bw) Sin. The excretion and pharmacokin...
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Owing to the excellent performances of high sensitivity, high specificity, on-site detection, and multiplexing capability, surface-enhanced Raman scattering (SERS)-based aptasensors have performed prosperous applications and gained impressive progress in food safety. Herein, we reviewed the SERS-based aptasensors from the principles to specific applications in food safety. First, the sensor-working principles, SERS label design and preparation are introduced. Then, the popular platforms in the a...
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#1Qiong Lu (DUT: Dalian University of Technology)H-Index: 1
#2Liping Xu (CAS: Chinese Academy of Sciences)
Last. Qing Yang (DUT: Dalian University of Technology)H-Index: 25
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Insect group h chitinase is a promising target for designing non-target safe pesticides in that it is exclusively distributed in lepidopteran insects, over 80% of which are agricultural pests. In this work, lynamicin B was discovered to be an inhibitor of OfChi-h, the group h chitinase from the lepidopteran pest Ostrinia furnacalis. Lynamicin B was revealed to competitively inhibit OfChi-h with a Ki value of 8.76 μM and does not significantly inhibit other chitinases. The co-crystal structure of...
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#1Da-Wei Wang (NKU: Nankai University)H-Index: 10
#2Hang Zhang (NKU: Nankai University)H-Index: 2
Last. Zhen Xi (NKU: Nankai University)H-Index: 31
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A key objective for herbicide research is to develop new compounds with improved bioactivity. Protoporphyrinogen IX oxidase (PPO) is an essential target for herbicide discovery. Here, we report using an in silico structure-guided optimization approach of our previous lead compound 1 and designed and synthesized a new series of compounds 2-6. Systematic bioassays led to the discovery of a highly potent compound 6g, 1-methyl-3-(2,2,7-trifluoro-3-oxo-4-(prop-2-yn-1-yl)-3,4-dihydro-2H-benzo[b][1,4]o...
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#1Jing Li (HZAU: Huazhong Agricultural University)H-Index: 24
#2Qinghui Li (HZAU: Huazhong Agricultural University)H-Index: 3
Last. Mingle Wang (HZAU: Huazhong Agricultural University)H-Index: 4
view all 14 authors...
Magnesium (Mg) plays important roles in photosynthesis, sucrose partitioning, and biomass allocation in plants. However, the specific mechanisms of tea plant response to Mg deficiency remain unclear. In this study, we investigated the effects of Mg deficiency on the quality constituents of tea leaves. Our results showed that the short-term (7 days) Mg deficiency partially elevated the concentrations of polyphenols, free amino acids, and caffeine but decreased the contents of chlorophyll and Mg. ...
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#1Wen Zhang (NFU: Nanjing Forestry University)H-Index: 4
#2Manman Shi (NFU: Nanjing Forestry University)
Last. Erzheng Su (NFU: Nanjing Forestry University)H-Index: 9
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4'-O-Methylpyridoxine (MPN) and MPN-5'-glucoside (MPNG) are collectively known as ginkgotoxin, which are the main toxic ingredients of excessive consumption of Ginkgo biloba seeds. Water extraction is the generally adopted sample preparation method for high-performance liquid chromatography determination of ginkgotoxin. However, endogenous enzymes such as glycosidases in Ginkgo biloba seeds can hydrolyze MPNG to MPN in the process of water extraction, which will result in the measured contents o...
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Ganoderic acid A (GAA) is a kind of lanostane-type triterpenoid isolated from Ganoderma lucidum. Imbalance of the Th17/Tregs axis exists in the progress of neuroinflammation of Alzheimer's disease (AD). In this study, the alleviating neuroinflammatory effect of GAA on d-galactose mice was studied from the aspect of regulating the imbalance of the Th17/Tregs axis. The Morris water maze test was used to evaluate the cognitive ability of AD mice. Flow cytometry was used to detect the percentages of...
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#1Xinlei Zhang (HFUT: Hefei University of Technology)H-Index: 1
#2Jianguo Xu (HFUT: Hefei University of Technology)H-Index: 17
Last. Wei Chen (HFUT: Hefei University of Technology)H-Index: 80
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Accurate and rapid quantification of foodborne pathogens is of great significance for food safety and human health. In this work, we have successfully constructed a fluorescence quenching collapsar probe (FQCP) on the basis of a conventional aptamer-encoded molecular beacon (AEMB) and applied it for the detection of Salmonella. In structure, the FQCP is assembled by AEMBs in fours via specific streptavidin and biotin binding. Such a simple format makes the FQCP cofunctionalized with short- and l...
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#1Carolina Alemán-Jiménez (UCAM: Universidad Católica San Antonio de Murcia)
#2Raúl Domínguez-Perles (CSIC: Spanish National Research Council)H-Index: 24
Last. Sonia Medina (CSIC: Spanish National Research Council)H-Index: 23
view all 10 authors...
Recently, new bioactive compounds were identified in olive oil, lipophenols, which are composed of a fatty acid (FA) and a phenolic core, such as HT (HT-FA). However, their bioaccessibility remains unknown. Thus, the present study uncovers the impact of the separate phases of gastrointestinal digestion on the release and stability of HT-FAs from oily matrices under in vitro simulated conditions. Accordingly, it was found that the bioaccessibility of HT derivatives is largely dependent on the typ...
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#1Ting Li (SPU: Shenyang Pharmaceutical University)H-Index: 1
#2Xindi Zhang (SPU: Shenyang Pharmaceutical University)
Last. Xiangrong Zhang (SPU: Shenyang Pharmaceutical University)H-Index: 34
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The aim of this study was to fabricate ursolic acid (UA)-sodium alginate (SA) complexes to improve the dissolution rate and antioxidant abilities. The antioxidant activity was evaluated by the DPPH (1,1-diphenyl-2-trinitrophenylhydrazine) assay and the pyrogallol auto-oxidation method. For the optimal composition ratio of UA:SA (1:5, w/w), the cumulative release of UA was about 101.22 ± 1.50% for 180 min. Powder X-ray diffractometry (PXRD), differential scanning calorimetry (DSC), and scanning e...
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