VEGF/VEGFR2 blockade does not cause retinal atrophy in AMD-relevant models
Abstract
Intraocular injections of VEGF-neutralizing proteins provide tremendous benefits in patients with choroidal neovascularization (NV) due to age-related macular degeneration (AMD), but during treatment some patients develop retinal atrophy. Suggesting that VEGF is a survival factor for retinal neurons, a clinical trial group attributed retinal atrophy to VEGF suppression and cautioned against frequent anti-VEGF injections. This recommendation may...
Paper Details
Title
VEGF/VEGFR2 blockade does not cause retinal atrophy in AMD-relevant models
Published Date
May 17, 2018
Journal
Volume
3
Issue
10
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